Ronald D. Stall, professor focusing his work on AIDS and behavioral research, talks about the behavior changes within the homosexual community in the Castro District which had one of the highest HIV prevalences in North America in 1988.

XIX International AIDS Conference in Washington D.C. Brazilian musical performance Carnival Champs in Rhythm of Prevention.

Last part of the interview with the American AIDS activist and founder of Project Inform, Martin Delaney, in 2006. Here he talks about AIDS activism and the different stages of the antiretroviral drug development from AZT to triple combination treatment.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.

Students are interviewed on the street in Washington DC, about HIV/AIDS and prevention.

Continuation of the interview with Elaine and her husband Hubby. They talk about their HIV diagnoses and relationship as a married couple, about safe sex as prevention of AIDS disease progression, and workplace discrimination.