XIX International AIDS Conference in Washington D.C. Barton Haynes from the Duke Human Vaccine Institute (DHVI) has been working in the HIV vaccine field since 1985. Here he talks about the scientific difficulties of finding an HIV vaccine.

XIX International AIDS Conference. Matias Ostrowski from University of Buenos Aires is part of the CNIHR program lead by IAS and NIH. He is involved in basic research on the cell biology of HIV with the target of creating new ideas for drug development.

XIX International AIDS Conference. Session focusing on the scientific strategies in HIV cure research, ethical questions in clinical HIV cure trials and the patient benefits of those clinical trials. The panel members are scientists and physicians, activists and long-term survivors.

XIX International AIDS Conference. Lecture on SAMHD1 proteins by a scientist from the French vaccine research institute ANRS. The French Minister of Higher Education and Research holds a speech about the French-American collaboration in vaccine research.

XVII International AIDS Conference in Mexico City. Dr Daria Hazuda from MSD, who has been involved in antiretroviral drug development during the past 20 years, holds a presentation. She is also interviewed about leadership and the progress of ARV and vaccine development.

French virologist and Nobel Prize winner Luc Montagnier reflects on the discovery of HIV, discusses disappointments and lessons learned along the way and the possibility of a vaccine, and gives advice for future AIDS researchers.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.