This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

Quarraisha Abdool Karim is an epidemiologist in Durban. She talks about the start of the South African AIDS epidemic and the South African AIDS response, health policies and campaigns. She explains why women are more susceptible to HIV than men are.

Dr Ingrid van Beek from the Sydney Medically Supervised Injecting Centre (MSIC), a program offering HIV testing, counseling, needle-exchange and methadone programs. She talks about the challenges and successes of the Australian AIDS response.

Dale Rogers is a lab assistant at San Francisco General Hospital. Here he talks about the relationship between health personnel and AIDS patients and how working with young AIDS patients affects his life. He also talks about stigma among health personnel.

Interview with Agneta Dreber from Folkhälsomyndigheten (National Institute of Public Health) in Sweden. She talks about the Swedish HIV/AIDS situation, about sexuality education in schools and HIV/AIDS education in workplaces.

Praphan Phanupak, co-founder of the Thai Red Cross AIDS Research Center (TRC-ARC) and Professor at the Chulalongkorn University Hospital, tells about his encounter with the first AIDS patient in Thailand, about the health resources in Thailand and about stigma.