The Swedish professor Emeritus in Infectious Diseases at Karolinska Institutet is interviewed about his memories and work as infectious disease physician in the 1980’s.

Interview with David Cooper, Director of The Kirby Institute at the University of New South Wales.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

Lars Olof Kallings talks about the global AIDS situation and what the international community can do. He reflects on the role of men, women and young people in the fight against AIDS, and stresses the importance of activists and voluntary organizations.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.