Ronald D. Stall, professor focusing his work on AIDS and behavioral research, talks about the behavior changes within the homosexual community in the Castro District which had one of the highest HIV prevalences in North America in 1988.

Two interviews with Dr Mervyn Silverman, from 1988 and 2008. He explains the San Francisco model, how it began and what others can learn from it.

American actress Sharon Stone talks about her memories of Rock Hudson and her work with amfAR. She reflects on AIDS and stigma, how to reach out to young people, and the importance of communication in order to change the sexual behaviors of young people.

First part of the interview with Tony Lisle, UNAIDS country coordinator in Cambodia. He talks about the difficult situation for men who have sex with men and male sex workers in Cambodia.

Erica Chilua Missis Gonde is a counselor and teacher involved in the local HIV/AIDS response in Kafue District in the Lusaka province. In this interview she talks about women's health and the importance of health education to change male sexual behavior.

The 21 years old Botswanan hip hop artist Oracle talks about social stigma, parent-child relations regarding AIDS, how to influence the young people in Botswana, the possibility of changing sexual behavior, and his thoughts on the origin of HIV/AIDS.

Lars Olof Kallings talks about the global AIDS situation and what the international community can do. He reflects on the role of men, women and young people in the fight against AIDS, and stresses the importance of activists and voluntary organizations.

Dr Selma Dritz tells the story of how the AIDS epidemic started in Los Angeles and San Francisco in the early 80's and how AIDS was connected to the gay liberation movement. She also talks about the government and community responses at that time.

Helene Gayle is an AIDS expert who has been working in many different initiatives in the US, among them the Centers for Disease Control (CDC). She also works in President Obama's advisory group on HIV/AIDS. Here she talks about understanding and changing behaviors.

Praphan Phanupak is Professor in Immunology and the Director of the Thai Red Cross AIDS Research Centre (TRC-ARC). He talks about the incidence and prevalence of HIV infection in different parts of Thailand and about human experiments on Thai drug users.

This production was made as the opening film for the IV International AIDS Conference in Stockholm in June 1988. It gives a broad representation of the global AIDS situation in the late 1980's, and has a particular focus on social structures, poverty and stigma.

Dr Robert Gallo is interviewed in the laboratory about the HIV virus and his ongoing work. He also talks with his team and discusses the question of international collaboration with Lars Olof Kallings. He answers questions about HIV and AIDS, drugs and promiscuity.