The Swedish professor Emeritus in Infectious Diseases at Karolinska Institutet is interviewed about his memories and work as infectious disease physician in the 1980’s.

Interview with the Scottish Singer and AIDS activist Annie Lennox in Mexico City. She talks about her activism and the situation of poverty, violence, gender inequality and human rights violations connected with HIV/AIDS.

Interview with the Scottish Singer and AIDS activist Annie Lennox in Mexico City. She talks about her activism and the situation of poverty, violence, gender inequality and human rights violations connected with HIV/AIDS.

XVII International AIDS Conference in Mexico City. Ending of a panel session on the vaccine trials of the International AIDS Vaccine Initiative (IAVI). Seth Berkley, Alan Bernstein and Omu Anzala respond to questions from the audience.

XVII International AIDS Conference in Mexico City. Panel discussion with Annie Lennox, among others, on global health policy and how the HIV/AIDS situation affects African communities.

XVII International AIDS Conference in Mexico City. Cutaways of panel discussions with Annie Lennox and members of Oxfam International, among others, on global health policy and how the HIV/AIDS situation affects African communities.

Interview with Daniel Tarantola, Professor of Health and Human Rights at University of New South Wales in Sydney. He tells about his work in expanding health care services in several African countries, starting in the early 1970's and the time when he entered the HIV field.

French virologist and Nobel Prize winner Luc Montagnier reflects on the discovery of HIV, discusses disappointments and lessons learned along the way and the possibility of a vaccine, and gives advice for future AIDS researchers.

Interview with Pathologist Christian Isichei, founder of the Faith Alive Hospital in Jos in Nigeria. He talks about the drug industry and access to ARV treatment in Africa and his experiences from the annual conference at the Institute of Human Virology (IHV) in Baltimore.

Luc Montagnier talks about the complex virology of HIV which makes the AIDS vaccine development so difficult. He also talks about the economic and cultural advantages of using traditional medicine as a part of the ARV therapy in developing countries.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.