XVII International AIDS Conference in Mexico City. Interview with Edwin Nichols who works at the World AIDS Campaign (WAC) a cross-national organization, initially governed by UNAIDS, working with campaigns to influence political decision makers on HIV/AIDS issues.

XVII International AIDS Conference in Mexico City. Interview with Paul Bekkers who is the AIDS Ambassador for the Netherlands. He talks about national leadership in the global response to HIV and AIDS, about youth and sexuality education.

Mr Subbarao is secretary of state for health in the Tamil Nadu Government in Chennai. In this interview he talks about the educational and medical work lead by the government. He talks particularly about empowering and educate women about HIV prevention.

XV International AIDS Conference in Bangkok in July, 2004. Interview with Swedish AIDS Ambassador Lennart Hjelmåker. He talks about the global HIV and AIDS situation, about what is being done and what is to be done by communities and governments in the future.

A film documenting the situation in Russia in 2002, highlighting the conflict between different approaches to the HIV problem.

Quarraisha Abdool Karim is an epidemiologist in Durban. She talks about the start of the South African AIDS epidemic and the South African AIDS response, health policies and campaigns. She explains why women are more susceptible to HIV than men are.

Students are interviewed on the street in Washington DC, about HIV/AIDS and prevention.